The application of physical, mathematical and engineering concepts to the improvement of clinical practice is a challenging task. This meeting aims to bring together researchers from different fields of cardiovascular fluid dynamic research with the goal of characterizing and advancing work that addresses real clinical needs. Topics include: fluid dynamics of the heart, large arteries and microcirculation, effect of prosthesis and surgical procedures on flow, multi-scale models and networks. Presentations are expected to cover theoretical aspects, computational models, and experimental techniques, including clinical measurements and interfacing with medical imaging. Discussions are planned towards improved interaction with clinical researchers.